Multifunctional materials with hydrophobic and/or hydrophilic properties are often found in nature, and bioinspired surfaces are being explored extensively for industrial and biomedical applications to control cell growth, harvest and/or transport water, self-clean, or even self-heal. This project describes the effects of dielectric barrier discharge (DBD) plasmas on the surface wettability of variety of polymers, including polymethyl methacrylate (PMMA) and Teflon. The plasma forms into self-organizing streamers that modify the surface chemistry and microstructure of the polymer. Experimentation is focused on how to localize plasma treatment with reproducible patterns and surface properties. In this project, we investigate how different combinations of plasma parameters, namely frequency/voltage, gas atmosphere, and pressure affect surface properties of the plasma treatment materials. Another point of interest is how the pattern of the streamers can be tuned by using a patterned (specifically machined) dielectric. Water contact angle (WCA) is used to analyze the areas treated by plasma to characterize wetting properties of surfaces. Optical microscopy is used to investigate surface topography before and after plasma treatment. Preliminary results of DBD plasma treatment of PMMA polymer (WCA=75o for pristine polymer) show that WCA ranges from 30^o - 90^o showing both hydrophobic and hydrophilic properties after treatment. Furthermore, a high-speed camera is used to capture the plasma pattern at short treatment times and subsequently it will be correlated with the wetting profile of the sample. Results show that both the surface chemistry and surface roughness are seen to change due to the impact of plasma. A ‘catalog’ of the plasma patterns provides information about how the patterning is affected by the various plasma parameters that go into treatment.